Using Watchtower for approximately 2 years on about 20 Containers. I had 1 issue, where a container would not start after the update. The Error Message said I had an unsupported entry in the configuration file of the app. I looked up the changelog of that app, and found out that the option was removed and replaced by something else. Had to change one line in the configuration. Not really a problem for me.
Though I decided to exclude my Home Automation Container and my kasm container ( my gateway to my network, a bit like guacamole ). Those may pose problems if they are offline unexpected.
What does Vega drivers have to do with these CPUs? Vega are GPUs.