Depends on how much memory you want to get. I’m running 4 channel x 32gb (128gb total) on an Asus strix z790-e wifi, and it’s unsupported. I can’t get it to post at the rated 6000mhz, so I underclocked it to 5066 (it does post up to 5200mhz but 5200mhz shows errors in memtest386). At 5066mhz it runs all 4 passes of memtest86 cleanly.

It’s gskill 6000mhz z5.memoey.

I did try corsair dominators (24gb each x 4 channel) and they wouldn’t post at their rated 7000mhz either. But even underclockibg them at 4800mhz was unstable.

My advice is to stay with dual channel if you can, as those have more luck posting at xmp speeds.

There was no valid supported 32gb x 4 channel config from the manufacturer so I’m lucky it works at all. I had to have 128gb of RAM though so put up with the slightly slower speeds.

Asus lists the manufacturers and combinations certified to work with the board on the boards support page. Stick with those if you want xmp to work and not have to figure out a stable setup yourself.