Bonus panel:
No no you see it’s…it’s all made of vibrating… energy, no not like that, in a science way! There’s particles, but actually they’re waves, but of probability but its all energy. What is energy? Uh… work, over time. What’s work? Uh… the thing I really better get back to, bye!
its all energy. What is energy? Uh…
This. This so much. What the hell is energy and what enables it to exist?
Heat, movement, radiation, mass.
Heath
Not native language.
Sorry, I didn’t mean to criticize you, it’s just a joke.
It’s alright.
No heat, no radiation, no mass anymore, so heath is a vacuum?
deleted by creator
What’s heat, precious?
energy is what scientists never have enough of and its existence is enabled purely by being able to observe yourself not having enough of it
As I recall it, energy is motion.
In a way. I mean we know it exists, no one would reasonable deny it, but the exact mechanism are still debated. How much is beneficial adaptation, how much is genetic drift for example. But the common ancestry is as common sense as that an apple will fall to earth
I thought it was pretty well accepted that it’s basically “Genetic defects happen, sometimes they don’t prevent reproduction and pass down to the next generation, then it’s a lottery, maybe it will last, maybe it won’t, maybe it’s beneficial, maybe it isn’t 🤷”
Maybe at some point a human was born with knees that would never wear out but they died before having the chance to reproduce from being eaten by a tiger, we’ll never know!
Except that horizontal gene transfer happens.
Genes are not always gained from ancestors
bacteria and some others, preparing for horizontal gene transfer: “im about to ruin man(kind)'s whole career”
Yeah the real issue in a way is that there’s just so much evidence of evolution happening that it’s hard to find a single shared pattern to study
The pioneers in some fields are calling for studying (or renaming it) INvolution as opposed to evolution, as it has much to do with involved interactions with other life forms (bacterial, fungal).
I mean do we understand evolution better than gravity?
The last panel indicates someone at the bleeding edge of science, at that level too, surely there’s mystery in biology as well?
i would say yes. there likely isn’t going to be some fundamental re-thinking of evolution. sure, there are details and interactions we surely don’t know about yet, but the general principles and mechanisms are astoundingly clear.
on the other hand, gravity is central to the problem of combining general relativity and the standard model. so afaik, something significant will need to change in at least one of them to resolve the issue of gravity. so we know we have a pretty massive gap in our understanding somewhere.
Is that really the case? I’m a layman so I may fuck this up - but do we truly understand why the locus of an allelomorph can change and how and why which phenotypic traits are affected or unaffected by addition and deletion?
I get the impression there is not model for why sometimes thousands of base pairs can fuck off with no impact, and sometimes it changes the organism unrecognizably.
The theory does not need to explain why. It needs to explain how, and prove that it’s happening. We know how traits change over time to form new species, and we know that this does in fact happen. There’s always more to learn about specifics, but it’s almost certainly not changing that evolution is happening, and the mechanisms for that are pretty well understood.
I get the impression there is not model for why sometimes thousands of base pairs can fuck off with no impact, and sometimes it changes the organism unrecognizably.
No there’s many known reasons that can happen. Here’s just some of them, but in the end it all comes down to understanding that genes code for proteins, little molecular machines. Sometimes there are multiple copies of genes that code for similar proteins or even the same protein, so losing one or even more doesn’t really do anything as there’s more where that came from. Sometimes there are genes that used to be important but no longer have a role or were made redundant, and are free to sedit. If a gene codes for a protein called an enzyme, sometimes a change in the active site that binds the chemicals for the reaction it assists might be catastrophic, but a change elsewhere doesn’t do much because it’s not as necessary to the function of the protein. Sometimes changes even result in the a similar amino acid or the exact same amino acid getting put at thag spot (since the genetic code has some redundancies, a different combo might still end up being the same).
Many genes code for proteins called transcription factors. Transcription factors help control expression of many other genes, some of which might also be transcription factors that in turn affect other genes, etc. This can create huge cascades. For instance there are things called hox genes that are very important for creating a cascade that leads to the formation of different body segments, and differentiating the different body segments. Mutations in these genes can be devastating, in some animals leading to the dissappearance or redundant addition of whole body segments.
There is tons more to learn of course on specifics in terms of evolution, genetics, and molecular biology of course. I don’t think it’s comparable to gravity though, which we seem to have a fundamental gap and irreconcilable theories.
At least coming from a background of life sciences personally, it seems to me evolution is probably better understood than gravity. I think a better comparison to gravity in the life sciences might be abiogenesis (how pre life conditions give rise to life to begin with). Once life is going, evolution, that we have a ton on. Not that we know nothing about abiogenesis, but that it’s a difficult outstanding problem.
am biologist who used to work in phylogenetics lab
there is a lot of fucking mystery
In the details or the fundamentals? Because Physics has the tiny problem that if our gravity models were correct, that would mean that we don’t know where like 95% of our galaxy’s mass is
Both details and fundamentals. And when the fundamentals get questioned things get dramatic. In like, an irritating way that reminds me of religious zealotry, uuuuuuugh
The "where is 95% of all the mass!?" seems a bit more dramatic in the grand scheme of things though, damn.
I witnessed grown adults outright bully teenage and young adult interns and grad students for presenting solid evidence that challenges paradigms (you know, like how we advance our understanding of science…?) but I can’t imagine it’s much better if everyone regardless of experience is just staring into a void of conflicting observations and nobody knows what the fuck any of it means
you know, like how we advance our understanding of science…?
One eulogy at a time, if you are of the Kuhn persuasion.
That was great. :)
We are all just part of the first self-replicating cell with funny mutations attracted to mass
Come on now. We all know that evolution is the expination to gravity! Look, all things that does not fall down, fall into space and die, hence only the things falling down to earth can live on and reproduce! Gravity is an emergent propery of evolution! Duh!